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抑制剂 & 化合物

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天然产物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T35450 α-GalCer analog 8

α-GalCer analog 8,α-Galactosylceramide analog 8

α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 &#181g per animal dose, indicati...
T38008 KBC-007

KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3 NKT hybridoma cells co-cultured with CD1d-transfected RBL cells pre-loaded with KBC-007 at a concentration of 8 ng/ml. KBC-007 (1 μg per animal) increases levels of IL-4, but not IFN-γ, to a similar degree as α-GalCer in mouse serum. KBC-007 (0.5 μg per animal) increases the sur...

化合物

α-GalCer analog 8
Cat.No: T35450
Synonym: α-GalCer analog 8,α-Galactosylceramide analog 8
Target:
KBC-007
Cat.No: T38008
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T14193 α-Galactosylceramide

KRN7000,α-GalCer

Others Others
α-Galactosylceramide (KRN7000) 是一种具有抗肿瘤和免疫刺激作用的合成糖脂。它是一种高效的 NKT 细胞激动剂,可与 CD1d 有效结合。它与 CD1d 的复合物可与 NKT 细胞的 T 细胞抗原受体结合。
T38285 C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

Others Others
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))是成熟髓鞘中主要的硫酸盐类化合物。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) 在大鼠小脑中发现活跃的髓发生鞘化反应时积累率高于C24 3'-sulfo 半乳糖甘油酰胺。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))与C 型凝集素和免疫球蛋白样受体相互作用使对LMIR5的亲和力高。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))诱导嗜碱细胞产生MCP-1,可通过增加LMIR5激活NFAT,但不能诱导肥大细胞 。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))在体外与CD1d 结合,并增加游离小鼠脾细胞的增殖。

天然产物

α-Galactosylceramide
Cat.No: T14193
Synonym: KRN7000,α-GalCer
Target: Others
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))
Cat.No: T38285
Synonym: C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))
Target: Others
Cat. No. Product Name Species Expression System
TMPY-02854 CD1D & B2M Heterodimer Protein, Human, Recombinant (His)

CD1D & B2M Heterodimer

Human HEK293 Cells
CD1D & B2M Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45 kDa and the accession number is P15813&P61769.
TMPY-01397 CD1D Protein, Mouse, Recombinant (His)

Cd1d,Cd1a,CD1d ...

Mouse HEK293 Cells
CD1D Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.7 kDa and the accession number is A0A0R4J090.
TMPY-04117 CD1D Protein, Mouse, Recombinant (His & hFc)

CD1.1,Cd1a,Cd1d,CD

Mouse HEK293 Cells
CD1D Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 60.4 kDa and the accession number is A0A0R4J090.
TMPY-05035 CD1D1 & B2M Heterodimer Protein, Mouse, Recombinant (His)

Mouse HEK293 Cells
CD1D1 & B2M Heterodimer Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.4 kDa and the accession number is NP_031665.2&P01887.
TMPY-04741 CD1D2 & B2M Heterodimer Protein, Mouse, Recombinant (His)

CD1D2 & B2M

Mouse HEK293 Cells
CD1D2 & B2M Heterodimer Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.4 kDa.

重组蛋白

CD1D & B2M Heterodimer Protein, Human, Recombinant (His)
Cat.No: TMPY-02854
Species: Human
Expression System: HEK293 Cells
CD1D Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01397
Species: Mouse
Expression System: HEK293 Cells
CD1D Protein, Mouse, Recombinant (His & hFc)
Cat.No: TMPY-04117
Species: Mouse
Expression System: HEK293 Cells
CD1D1 & B2M Heterodimer Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05035
Species: Mouse
Expression System: HEK293 Cells
CD1D2 & B2M Heterodimer Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04741
Species: Mouse
Expression System: HEK293 Cells
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